Edit |   |
---|---|
Antigenic Specificity | GP6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1.4 mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total GP6 protein. This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Immunogen | Immunogen: Synthetic peptide of human GP6 Immunogen Type: Peptide |
Other Names | [GPIV; GPVI; BDPLT11] |
Gene, Accession # | [GP6], Gene ID: 51206, NCBI: NP_001077368.2, UniProt: Q9HCN6 |
Catalog # | MBS9430564 |
Price | $255 |
Order / More Info | GP6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |