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Antigenic Specificity | GDNF - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene may be associated with Hirschsprung disease. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GDNF |
Other Names | [glial cell line-derived neurotrophic factor isoform 1 preproprotein; Glial cell line-derived neurotrophic factor; glial cell line-derived neurotrophic factor; glial cell derived neurotrophic factor; Astrocyte-derived trophic factor] |
Gene, Accession # | [GDNF], Gene ID: 2668, NCBI: NP_000505.1, UniProt: P39905 |
Catalog # | MBS3221246 |
Price | $335 |
Order / More Info | GDNF - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |