PKD(PKCmu) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPKD(PKCmu)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionRabbit polyclonal to PKD/PKCmu). Activation of PKC is one of the earliest events in a cascade leading to a variety of cellular responses such as secretion, gene expression, proliferation and muscle contraction (1,2). Protein kinase D (PKD), also called PKCu, is a serine/threonine kinase whose activation is dependent on the phosphorylation of two activation loop sites, Ser744 and Ser748, via a PKC-dependent signaling pathway (3-5). In addition to the two activation loop sites, the carboxy-terminal Ser916 has been identified as an autophosphorylation site for PKD/PKCu. Phosphorylation at Ser916 correlates with PKD/PKCu catalytic activity (6).
ImmunogenImmunogen: A synthetic -peptide of human PKD/PKCmu
Other Names[PRKD1; PKD/PKCmu; PKD/PKCmu; PRKD1, PKC-MU, PKCM, PKD, PRKCM, Serine/threonine-protein kinase D1, Protein kinase C mu type, Protein kinase D, nPKC-D1, nPKC-mu], [PRKD1; PRKD1; PKD; PKCM; PRKCM; PKC-MU; PKD; PKD1; PRKCM]
Gene, Accession #Gene ID: 5587, NCBI: NP_002733.2, UniProt: Q15139
Catalog #MBS125854
Price$275, $430, $655
Order / More InfoPKD(PKCmu) Antibody from MYBIOSOURCE INC.
Product Specific References1. Nishizuka, Y. (1984) Nature 308, 693-698. 2. Keranen, L.M. (1995) Curr. Biol. 5, 1394-1403. 3. Valverde, A.M. et al. (1994) Proc. Natl. Acad. Sci. 91, 8572-8576. 4. Johannes, F.J. et al. (1994) J. Biol. Chem. 269, 6140-6148. 5. Iglesias, T. et al. (1998) J. Biol. Chem. 273, 27662-27667. 6. Matthews, S.A. et al. (1999) J. Biol. Chem. 274, 26543-26549. 7. Wood, C.D. et al. (2005) J Biol Chem 280, 6245-51.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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