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Antigenic Specificity | NCF4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total NCF4 antibody. The protein encoded by this gene is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI(3) k |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human NCF4. |
Other Names | [MGC3810; NCF; P40PHOX; SH3PXD4] |
Gene, Accession # | [NCF4], Gene ID: 4689, NCBI: NP_000622.2, UniProt: Q15080 |
Catalog # | MBS9400930 |
Price | $255 |
Order / More Info | NCF4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |