WTAP Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityWTAP
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
FormatProtein G purified
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionRegulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing, processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle (PubMed: 24316715, PubMed: 24407421, PubMed: 24981863). Acts as a mRNA splicing regulator (PubMed: 12444081). Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability (PubMed: 17088532). Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes (PubMed: 17095724).
ImmunogenImmunogen: Recombinant Human Pre-mRNA-splicing regulator WTAP protein (1-151AA)
Other Names[Pre-mRNA-splicing regulator WTAP; Female-lethal(2)D homolog; hFL(2)D; WT1-associated protein; Wilms tumor 1-associating protein; WTAP; KIAA0105]
Gene, Accession #[WTAP], Gene ID: 9589, NCBI: NP_001257460.1, UniProt: Q15007
Catalog #MBS7050204
Price$160, $235
Order / More InfoWTAP Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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