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Antigenic Specificity | Phospho-LAT-Y171 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding Y171 of human LAT Immunogen Species: Human |
Other Names | [IMD52; LAT1; pp36] |
Gene, Accession # | [LAT-Y171], Gene ID: 27040, NCBI: NP_001014987.1, UniProt: O43561 |
Catalog # | MBS9135662 |
Price | $235, $350, $525 |
Order / More Info | Phospho-LAT-Y171 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |