8-Oxoguanine DNA Glycosylase Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | 8-Oxoguanine DNA Glycosylase |
| Clone | [CPTC-OGG1-1] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2c, kappa |
| Format | purified |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: 8-oxoguanine (8-oxoG), an oxidized form of guanine, is produced by reactive oxygen species in both DNA and nucleotide pools during normal aging. Accumulation of 8-oxoG increases the occurrence of A:T to C:G or G:C to T:A transversionmutations, because 8-oxoG forms a stable basepair with adenine as well as with cytosine. OGG1 (for 8-oxoG DNA glycosylase), also designated MMH, is a DNA repair enzyme that corrects these mutations. Inactivation of the OGG1 gene leads to a mutator phenotype, characterized by the increase in G:C to T:A transversions. The OGG1 gene encodes eight isoforms (OGG1A-C, OGG2A-E) which result from alternative splicing of a single messenger RNA. The OGG1A splice variant is the most prevalent form and localize |
| Immunogen | Immunogen: Recombinant full-length human OGG1 protein |
| Other Names | [HMMH; HOGG1; MUTM; OGH1] |
| Gene, Accession # | [OGG1], Gene ID: 4968, NCBI: BAA76639.1, UniProt: O15527 |
| Catalog # | MBS4381139 |
| Price | $190, $340, $340 |
| Order / More Info | 8-Oxoguanine DNA Glycosylase Antibody from MYBIOSOURCE INC. |
| Product Specific References | Cheng, K.C., et al. 1992. J. Biol. Chem. 267: 166-17 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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