CUL5 (C-term), 747-774 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | CUL5 (C-term), 747-774 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: rabbit) |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 2 |
| Applications | Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This CUL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 747-774 amino acids from the C-terminal region of human CUL5. CUL5 is a core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAk2. It seems to be involved poteosomal degradation of p53/TP53 stim |
| Immunogen | n/a |
| Other Names | [Cullin-5; CUL-5; Vasopressin-activated calcium-mobilizing receptor 1; VACM-1; CUL5; VACM1] |
| Gene, Accession # | [CUL5], Gene ID: 8065, NCBI: NP_003469.2, UniProt: Q93034 |
| Catalog # | MBS9212647 |
| Price | $165, $370 |
| Order / More Info | CUL5 (C-term), 747-774 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Kamura T., Burian D., Yan Q.J. Biol. Chem. 276:29748-29753(2001) Mehle A., Goncalves J., Santa-Marta M.Genes Dev. 18:2861-2866(2004) Kamura T., Maenaka K., Kotoshiba S.Genes Dev. 18:3055-3065(2004) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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