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Antigenic Specificity | Spectrin beta III (SPTBN2) |
Clone | [SPTBN2/2887R] |
Host Species | Rabbit |
Reactive Species | human. |
Isotype | IgG |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Immunofluorescence (IF), Western Blot (WB), Immunohistology (Formalin-Fixed) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II), four beta-subunits (beta-I-beta-IV) and a beta-H subunit creating diversity and specialization of function. Spectrin alpha and spectrin beta are present in erythrocytes, whereas spectrin alpha II (also designated fodrin alpha) and spectrin beta I (also designated fodrin beta) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Spectrin beta III is highly ho |
Immunogen | Immunogen: Recombinant human SPTBN2 fragment (aa356-475) (exact sequence is proprietary) Positive Control: HeLa Cells. Pancreas or Liver. |
Other Names | [Beta III spectrin; SCA5; Spectrin beta chain brain 2; Spectrin beta non-erythrocytic 2; Spectrin non-erythroid beta chain 2; Spinocerebellar ataxia 5; SPTBN2] |
Gene, Accession # | [SPTBN2], Gene ID: 6712, NCBI: NP_008877.1, UniProt: O15020 |
Catalog # | MBS4380696 |
Price | $190, $340, $340 |
Order / More Info | Spectrin beta III (SPTBN2) Antibody from MYBIOSOURCE INC. |
Product Specific References | Speicher, D.W. 1986. J. Cell. Biochem. 30: 245-258. |