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Antigenic Specificity | Aquaporin 4 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The Aquaporin 4 mouse monoclonal antibody can detect endogenous Aquaporin 4 proteins. Description: Aquaporin 4 belongs to the Aquaporin family of integral membrane proteins that conduct water through the cell membrane.Function: Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system.Subunit Structure: Homotetramer. Part of a complex containing MLC1, TRPV4, HEPACAM and ATP1B1.Post-translational Modifications: Phosphorylation by PKC at Ser-180 reduces conductance by 50%. Phosphorylation by PKG at Ser-111 in response to glutamats increases conductance by 40% (By similarity).Similarity: Aquaporins contain two tandem repeats each containing three me |
Immunogen | Immunogen: Mouse monoclonal antibody is prepared by immunizing synthetic peptide coupled to KLH. Subcellular Location: Membrane. Tissue Specificity: Brain-muscle > > heart, kidney, lung, and trachea. |
Other Names | [AQP 4; AQP-4; AQP4; AQP4_HUMAN; Aquaporin type 4; Aquaporin-4; Aquaporin4; HMIWC 2; HMIWC2; Mercurial insensitive water channel; Mercurial-insensitive water channel; MGC22454; MIWC; WCH 4; WCH4] |
Gene, Accession # | Gene ID: 361, NCBI: NP_001641.1, UniProt: P55087 |
Catalog # | MBS9602849 |
Price | $235, $295, $370 |
Order / More Info | Aquaporin 4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |