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Antigenic Specificity | IL12RB2 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, porcine, rabbit, rat, sheep |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against IL12RB2. It was validated on Western BlotTarget Description: The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human IL12RB2 |
Other Names | [interleukin-12 receptor subunit beta-2 isoform a; Interleukin-12 receptor subunit beta-2; interleukin-12 receptor subunit beta-2; interleukin 12 receptor subunit beta 2] |
Gene, Accession # | [IL12RB2], Gene ID: 3595, NCBI: NP_001550, UniProt: Q99665 |
Catalog # | MBS3207662 |
Price | $365 |
Order / More Info | IL12RB2 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |