BID Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | BID |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: BID antibody detects endogenous levels of total BID. Description: The BH3 domain-only protein, BID, a death agonist member of the Bcl-2/Bcl-xL family (1), is localized in the cytosolic fraction of cells as an inactive precursor (2, 3). Its active form is generated upon proteolytic cleavage by caspase-8 in the Fas signaling pathway. Cleaved BID translocates to mitochondria and induces cytochrome c release and mitochondrial damage (2-5). Thus, BID relays an apoptotic signal from the cell surface to mitochondria. However, the precise molecular mechanism for the translocation of the cleaved BID, and for the subsequent release of cytochrome c during apoptosis, is still unclear.Function: The major proteolytic product p15 BID allo |
| Immunogen | Immunogen: A synthesized peptide derived from human BID Subcellular Location: Cytoplasm; Cytoplasm. Mitochondrion Membrane. When uncleaved, it is predominantly cytoplasmic; mitochondrion membrane. A significant proportion of isoform 2 localizes to mitochondria, it may be cleaved constitutively; mitochondrion membrane. Associated with the mitochondrial membrane and mitochondrion membrane. Translocates to mitochondria as an integral membrane protein. Tissue Specificity: Isoform 2 and isoform 3 are |
| Other Names | [Apoptic death agonist; Apoptotic death agonist BID; BH3 interacting domain death agonist; BH3 interacting domain death agonist p11; BH3 interacting domain death agonist p13; BH3 interacting domain death agonist p15; BH3-interacting domain death agonist p11; BID; BID isoform ES(1b); BID isoform L(2); BID isoform Si6; BID_HUMAN; Desmocollin type 4; FP497; Human BID coding sequence; MGC15319; MGC42355; p11 BID; p13 BID; p15 BID; p22 BID] |
| Gene, Accession # | [BID], Gene ID: 637, NCBI: NP_001187.1, UniProt: P55957 |
| Catalog # | MBS9606684 |
| Price | $240, $280 |
| Order / More Info | BID Antibody from MYBIOSOURCE INC. |
| Product Specific References | Wang W, Liu X, Guo X, Quan H; Journal: Cell Physiol Biochem. Mitofusin-2 Triggers Cervical Carcinoma Cell Hela Apoptosis via Mitochondrial Pathway in Mouse Model. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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