MAPK8IP1 - N-terminal region Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | MAPK8IP1 - N-terminal region |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This gene encodes a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes. |
| Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAPK8IP1 |
| Other Names | [C-Jun-amino-terminal kinase-interacting protein 1; C-Jun-amino-terminal kinase-interacting protein 1; C-Jun-amino-terminal kinase-interacting protein 1; mitogen-activated protein kinase 8 interacting protein 1; Islet-brain 1; IB-1; JNK MAP kinase scaffold protein 1; Mitogen-activated protein kinase 8-interacting protein 1] |
| Gene, Accession # | [MAPK8IP1], Gene ID: 9479, NCBI: NP_005447.1, UniProt: Q9UQF2 |
| Catalog # | MBS3219969 |
| Price | $335 |
| Order / More Info | MAPK8IP1 - N-terminal region Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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