EPHA8 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityEPHA8
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: EPHA8 antibody detects endogenous levels of EPHA8. Function: Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. The GPI-anchored ephrin-A EFNA2, EFNA3, and EFNA5 are able to activate EPHA8 through phosphorylation. With EFNA5 may regulate integrin-mediated cell adhesion and migration on fibronectin substrate but also neurite outgrowth. During development of the nervous system plays also a role in axon guidance.
ImmunogenImmunogen: A synthesized peptide derived from human EPHA8 Subcellular Location: Endosome; Plasma Membrane
Other Names[ephrin type-A receptor 8 isoform 2; Ephrin type-A receptor 8; ephrin type-A receptor 8; EPH receptor A8; EPH- and ELK-related kinase; EPH-like kinase 3; EK3; hEK3; Tyrosine-protein kinase receptor EEK]
Gene, Accession #[EPHA8], Gene ID: 2046, NCBI: NP_001006944.1, UniProt: P29322
Catalog #MBS9603189
Price$240, $280
Order / More InfoEPHA8 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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