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Antigenic Specificity | EPHA8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: EPHA8 antibody detects endogenous levels of EPHA8. Function: Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. The GPI-anchored ephrin-A EFNA2, EFNA3, and EFNA5 are able to activate EPHA8 through phosphorylation. With EFNA5 may regulate integrin-mediated cell adhesion and migration on fibronectin substrate but also neurite outgrowth. During development of the nervous system plays also a role in axon guidance. |
Immunogen | Immunogen: A synthesized peptide derived from human EPHA8 Subcellular Location: Endosome; Plasma Membrane |
Other Names | [ephrin type-A receptor 8 isoform 2; Ephrin type-A receptor 8; ephrin type-A receptor 8; EPH receptor A8; EPH- and ELK-related kinase; EPH-like kinase 3; EK3; hEK3; Tyrosine-protein kinase receptor EEK] |
Gene, Accession # | [EPHA8], Gene ID: 2046, NCBI: NP_001006944.1, UniProt: P29322 |
Catalog # | MBS9603189 |
Price | $240, $280 |
Order / More Info | EPHA8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |