Mouse CD107a/LAMP-1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse CD107a/LAMP-1 |
| Clone | [1D4B] |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2a kappa |
| Format | unconjugated |
| Size | 0.5 mg |
| Concentration | n/a |
| Applications | Flow Cytometry; Immunohistochemistry (Frozen Sections); Immunoprecipitation; Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Murine CD107a/LAMP-1 (Mr 110-140 kDa with a core protein of Mr ~40 kDa). CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated, type I transmembrane protein that constitutes one of the two major sialoglycoproteins on lysosomal membranes that can be used to distinguish lysosomes from other organelles.^1 It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains, and is a ligand for E-selectin-mediated cell adhesion.^2 CD107a is principally expressed in epithelial cells and macrophages in a variety of organs in normal and Beige mutant mice.^3 LAMP-1 may function in protecting the inner surface of the |
| Immunogen | Immunogen: Plasma membrane fraction of mouse embryo NIH3T3 cell line |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS673717 |
| Price | $290 |
| Order / More Info | Mouse CD107a/LAMP-1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Chen, J.W., W. Pan, M.P. d'Souza and J.T. August. 1985. Arch. Biochem. Biophys. 239:574.2. Arterburn, L.M., B.J. Earles, and J.T. August. 1990. J. Biol. Chem. 265:7419.3. Chen, J.W., G.L. Chen, M.P. d'Souza, T.L. Murphy, and J.T. August. 1986. Biochem. Soc. Symp. 51:97.4. Fukuda, M. 1991. J. Biol. Chem. 266:21327.6. Rohrer, J., A. Schweizer, D. Russell, and S. Kornfeld. 1996. J. Cell. Biol. 132:565. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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