IREB2 - middle region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIREB2 - middle region
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesdog, guinea pig, horse, human, mouse, porcine, rabbit, rat, zebrafish
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis is a rabbit polyclonal antibody against IREB2. It was validated on Western Blot using a cell lysate as a positive control.Target Description: IREB2 binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. IREB2 binds to the IRE element in ferritin which results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the middle region of human IREB2
Other Names[iron-responsive element-binding protein 2 isoform 1; Iron-responsive element-binding protein 2; iron-responsive element-binding protein 2; iron responsive element binding protein 2; Iron regulatory protein 2; IRP2]
Gene, Accession #[IREB2], Gene ID: 3658, NCBI: NP_004127, UniProt: P48200
Catalog #MBS3205284
Price$365
Order / More InfoIREB2 - middle region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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