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Antigenic Specificity | IREB2 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | dog, guinea pig, horse, human, mouse, porcine, rabbit, rat, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against IREB2. It was validated on Western Blot using a cell lysate as a positive control.Target Description: IREB2 binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. IREB2 binds to the IRE element in ferritin which results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human IREB2 |
Other Names | [iron-responsive element-binding protein 2 isoform 1; Iron-responsive element-binding protein 2; iron-responsive element-binding protein 2; iron responsive element binding protein 2; Iron regulatory protein 2; IRP2] |
Gene, Accession # | [IREB2], Gene ID: 3658, NCBI: NP_004127, UniProt: P48200 |
Catalog # | MBS3205284 |
Price | $365 |
Order / More Info | IREB2 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |