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Antigenic Specificity | MCL, Rat |
Clone | WEN42 |
Host Species | Mouse |
Reactive Species | rat |
Isotype | IgG2a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) Formalin, Flow Cytometry (FC/FACS), Functional Studies (FS), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The monoclonal antibody WEN42 recognizes rat macrophage C-type lectin (MCL). C-type lectin receptors (CLRs) have recently been identified as a fourth family of pattern-recognition receptors for pathogen associated molecular patterns, following TLRs, Nod-like receptors and RIG-I-like receptors. MCL is a membrane surface receptor encoded by the Antigen Presenting Lectin-like gene Complex (APLEC).The complex consists of seven related C-type lectin receptor genes, namely, Dendritic Cell Activating Receptor (DCAR), Dendritic Cell Inhibitory Receptor 1, 2, 3 and 24 (DCIR), Macrophage C-type lectin (MCL) and Macrophage inducible C-type lectin (Mincle). MCL is a type II transmembrane protein with a single extracellular C-terminal C-type lectin-like |
Immunogen | Immunogen: BWZ.36 cell expressing chimeric MCL |
Other Names | n/a |
Gene, Accession # | [MCL] |
Catalog # | MBS584777 |
Price | $470 |
Order / More Info | MCL, Rat Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Lobato-Pascual, A et al; Rat macrophage C-type lectin is an activating receptor expressed by phagocytic cells. PLoS ONE 2013, 8: e57406 2. Lobato-Pascual, A et al; Mincle, the receptor for mycobacterial cord factor, forms a functional receptor complex with MCL and FcepsilonRI-gamma. Eur J Immunol 2013, 43: 3167 |