MCL, Rat Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMCL, Rat
CloneWEN42
Host SpeciesMouse
Reactive Speciesrat
IsotypeIgG2a
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) Formalin, Flow Cytometry (FC/FACS), Functional Studies (FS), Immunoprecipitation (IP), Western Blot (WB)
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DescriptionThe monoclonal antibody WEN42 recognizes rat macrophage C-type lectin (MCL). C-type lectin receptors (CLRs) have recently been identified as a fourth family of pattern-recognition receptors for pathogen associated molecular patterns, following TLRs, Nod-like receptors and RIG-I-like receptors. MCL is a membrane surface receptor encoded by the Antigen Presenting Lectin-like gene Complex (APLEC).The complex consists of seven related C-type lectin receptor genes, namely, Dendritic Cell Activating Receptor (DCAR), Dendritic Cell Inhibitory Receptor 1, 2, 3 and 24 (DCIR), Macrophage C-type lectin (MCL) and Macrophage inducible C-type lectin (Mincle). MCL is a type II transmembrane protein with a single extracellular C-terminal C-type lectin-like
ImmunogenImmunogen: BWZ.36 cell expressing chimeric MCL
Other Namesn/a
Gene, Accession #[MCL]
Catalog #MBS584777
Price$470
Order / More InfoMCL, Rat Antibody from MYBIOSOURCE INC.
Product Specific References1. Lobato-Pascual, A et al; Rat macrophage C-type lectin is an activating receptor expressed by phagocytic cells. PLoS ONE 2013, 8: e57406 2. Lobato-Pascual, A et al; Mincle, the receptor for mycobacterial cord factor, forms a functional receptor complex with MCL and FcepsilonRI-gamma. Eur J Immunol 2013, 43: 3167
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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