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Antigenic Specificity | S100A9 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: S100A9 antibody detects endogenous levels of total S100A9. Function: S100A9 is a calcium-and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis, adhesion, can increase the bactericidal activity of neutrophils by promoting phagocytosis via activation of SYK, PI3K/AKT, and ERK1/2 and can induce degranulation of neutrophils by a MAPK-dependent mechanism. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra-and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration |
Immunogen | Immunogen: A synthesized peptide derived from human S100A9 Subcellular Location: Secreted. Cytoplasm. Cytoplasm > Cytoskeleton. Cell Membrane. Associates with tubulin filaments in activated monocytes. Targeted to the cell surface upon calcium influx. Released from blood leukocytes upon exposure to CSF2/GM-CSF, bacterial lipopolysaccharide (LPS) and during inflammatory processes. Serum levels are high in patients suffering from chronic inflammation. Tissue Specificity: Calprotectin (S100A8/9) is |
Other Names | [Leukocyte L1 complex heavy chain; 60B8AG; CAGB; Calgranulin B; Calgranulin-B; Calprotectin L1H subunit; CFAG; CGLB; Cystic fibrosis antigen B; L1AG; Leukocyte L1 complex heavy chain; LIAG; MAC387; MIF; Migration inhibitory factor related protein 14; Migration inhibitory factor-related protein 14; MRP 14; MRP-14; MRP14; Myeloid-related protein 14; NIF; OTTHUMP00000015331; p14; Protein S100-A9; S100 A9; S100 calcium binding protein A9; S100 calcium binding protein A9 calgranulin B; S100 calcium-binding protein A9; S100A9; S10A9_HUMAN] |
Gene, Accession # | [S100A9], Gene ID: 6280, NCBI: NP_002956.1, UniProt: P06702 |
Catalog # | MBS9608198 |
Price | $240, $280 |
Order / More Info | S100A9 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |