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Antigenic Specificity | MARCKS (C-term), 241-271 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MARCKS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 241-271 amino acids from the C-terminal region of human MARCKS. MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. |
Immunogen | n/a |
Other Names | [Myristoylated alanine-rich C-kinase substrate; MARCKS; Protein kinase C substrate; 80 kDa protein; light chain; 80K-L protein; PKCSL; MARCKS; MACS; PRKCSL] |
Gene, Accession # | [MARCKS], Gene ID: 4082, NCBI: NP_002347.5, UniProt: P29966 |
Catalog # | MBS9208395 |
Price | $165, $370 |
Order / More Info | MARCKS (C-term), 241-271 Antibody from MYBIOSOURCE INC. |
Product Specific References | Rauch, M.E., et al., J. Biol. Chem. 277(16):14068-14076 (2002). Aderem, A., Biochem. Soc. Trans. 23(3):587-591 (1995). Rao, P.H., et al., Cytogenet. Cell Genet. 66(4):272-273 (1994). Taniguchi, H., et al., J. Biol. Chem. 268(14):9960-9963 (1993). Blackshear, P.J., J. Biol. Chem. 268(3):1501-1504 (1993). |