Edit |   |
---|---|
Antigenic Specificity | SPPL3 (N-term), 50-81 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This SPPL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-81 amino acids from the N-terminal region of human SPPL3. Signal peptide peptidase (SPP) is an aspartyl protease that mediates clearance of signal peptides by proteolysis within the endoplasmic reticulum (ER). Like presenilins, SPP contains a critical GXGD motif in its C-terminal catalytic center. SPPL3 is one of several presenilin homologues/SPP-like proteins (PSHs/SPPL) that have been identified. |
Immunogen | n/a |
Other Names | [Signal peptide peptidase-like 3; SPP-like 3; 3423-; Intramembrane protease 2; IMP-2; Presenilin homologous protein 1; PSH1; Presenilin-like protein 4; SPPL3; IMP2; PSL4] |
Gene, Accession # | [SPPL3], Gene ID: 121665, NCBI: NP_620584.2, UniProt: Q8TCT6 |
Catalog # | MBS9203181 |
Price | $165, $370 |
Order / More Info | SPPL3 (N-term), 50-81 Antibody from MYBIOSOURCE INC. |
Product Specific References | Grigorenko, A.P., et al., Biochemistry Mosc. 67(7):826-835 (2002). Weihofen, A., et al., Science 296(5576):2215-2218 (2002). |