Edit |   |
---|---|
Antigenic Specificity | CHK1 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | 1ug/ul |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Active recombinant full length human CHK1 containing an Nterminal GST tag. This protein has an apparent molecular weight of ~82kDa. CHK1 appears to function downstream of several of the known fission yeast checkpoint gene products_recover, including that encoded by rad3+, a gene with sequence similarity to the ATM gene mutated in patients with ataxia telangiectasia. |
Immunogen | Immunogen: Ni-NTA purified recombinant protein CHK1 expressed in E Coli strain M15. |
Other Names | [Chk1; Serine/threonine-protein kinase Chk1; serine/threonine-protein kinase Chk1; checkpoint kinase 1; CHK1 checkpoint homolog; Cell cycle checkpoint kinase; Checkpoint kinase-1], [CHEK1; CHEK1; CHK1; CHK1] |
Gene, Accession # | [CHK1], Gene ID: 1111, NCBI: AAC51736.1 |
Catalog # | MBS418378 |
Price | $445 |
Order / More Info | CHK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. O'Connell, M.J. Chk1 is a Wee1 kinase in the G2 DNA damage checkpoint inhibiting Cdc2 by Y15 phosphorylation. EMBO J. 1998. 16: 545-554. 2. Matsuoka, S. Linkage of ATM to cell cycle regulation by the Chk2 protein kinase. Science 1998. 282: 1893-1897. |