Human CD282 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Human CD282 antibody, protein, ELISA kits.
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| Antigenic Specificity | Human CD282 |
| Clone | [4AT2.5] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 100 tests, 500 tests |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The 4AT2.5 monoclonal antibody reacts with mouse and human Toll-like receptor 2 (TLR2). Mouse TLR2 is expressed by the myeloid lineage, including macrophage and dendritic cells in splenocytes and the RAW264.7 cell line. To date, at least twelve members of the Toll family have been identified in human and mouse. This family of type I transmembrane proteins is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor. Two of these receptors, TLR2 and TLR4, are pattern recognition receptors and signaling molecules in response to bacterial lipoproteins and have been implicated in innate immunity and inflammation. TLR2 is expressed on the surface of cells and is responsi |
| Immunogen | n/a |
| Other Names | n/a |
| Gene, Accession # | [CD282] |
| Catalog # | MBS8502663 |
| Price | $280, $350 |
| Order / More Info | Human CD282 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1.Meng G, Rutz M, Schiemann M, Metzger J, Grabiec A, Schwandner R, Luppa PB, Ebel F, Busch DH, Bauer S, Wagner H, Kirschning CJ. 2004. Antagonistic antibody prevents toll-like receptor 2-driven lethal shock-like syndromes. J Clin Invest. 2004. 113:1473-81. 2.Sutmuller RP, den Brok MH, Kramer M, Bennink EJ, Toonen LW, Kullberg BJ, Joosten LA, Akira S, Netea MG, Adema GJ. Toll-like receptor 2 controls expansion and function of regulatory T cells.J Clin Invest. 2006 Feb; 116(2):485-94 (4AT2.5, FC, PubMed). 3.Leemans JC, Stokman G, et al. 2005. Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney. J Clin Invest. 2005 Oct; 115(10):2894-903. (IHC frozen and IP, PubMed). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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