Phospho-Nanog (S285) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Phospho-Nanog (S285) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Dot Blot (DB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Nanog Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S285 of human Nanog. NANOG is a Ttranscription regulator involved in inner cell mass and embryonic stem (ES) cels proliferation and self-renewal. It imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. This protein blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. NANOG acts as a transcriptional activator or repressor. It binds optimally to the DNA consens |
| Immunogen | n/a |
| Other Names | [Homeobox protein NANOG; Homeobox transcription factor Nanog; hNanog; NANOG] |
| Gene, Accession # | [NANOG], Gene ID: 79923, NCBI: NP_079141.2, UniProt: Q9H9S0 |
| Catalog # | MBS9211180 |
| Price | $165, $370 |
| Order / More Info | Phospho-Nanog (S285) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Kochupurakkal,B.S., Biochem. Biophys. Res. Commun. 365 (4), 846-850 (2008) Freberg,C.T., Mol. Biol. Cell 18 (5), 1543-1553 (2007) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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