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Antigenic Specificity | TIP60 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total TIP60 protein. Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damag |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human TIP60. |
Other Names | [EC 2.3.1.48; EC 2.3.1.-; 60 kDa Tat interactive protein; Tip60; HIV-1 Tat interactive protein] |
Gene, Accession # | [TIP60], Gene ID: 10524, NCBI: NP_001193762.1, UniProt: Q92993 |
Catalog # | MBS9401146 |
Price | $200, $255 |
Order / More Info | TIP60 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |