TIP60 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTIP60
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsImmunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total TIP60 protein. Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damag
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human TIP60.
Other Names[EC 2.3.1.48; EC 2.3.1.-; 60 kDa Tat interactive protein; Tip60; HIV-1 Tat interactive protein]
Gene, Accession #[TIP60], Gene ID: 10524, NCBI: NP_001193762.1, UniProt: Q92993
Catalog #MBS9401146
Price$200, $255
Order / More InfoTIP60 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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