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Antigenic Specificity | MKP-5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MKP-5 Polyclonal Antibody detects endogenous levels of MKP-5 protein. Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAP kinases, different tissue distribution and subcellular localization, and different modes of expression induction by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK. Alternative splicing results in multiple transcript variants. |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human MKP-5 at AA rangle: 330-410 |
Other Names | [Rabbit MKP-5; DUSP10; MKP5; Dual specificity protein phosphatase 10; Mitogen-activated protein kinase phosphatase 5; MAP kinase phosphatase 5; MKP-5] |
Gene, Accession # | [MKP-5], Gene ID: 11221, NCBI: NP_009138.1, UniProt: Q9Y6W6 |
Catalog # | MBS9704266 |
Price | $130, $220, $325 |
Order / More Info | MKP-5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |