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Antigenic Specificity | IGF-IR (Phospho Tyr1165/Y1166) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, monkey |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-IGF-IR (Y1165/Y1166) Polyclonal Antibody detects endogenous levels of IGF-IR protein only when phosphorylated at Y1165/Y1166. Insulin like growth factor 1 receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for IGF1R. |
Immunogen | Immunogen: Synthesized peptide derived from human IGF-IR around the phosphorylation site of Y1165/Y1166 |
Other Names | [Rabbit IGF-IR (phospho Tyr1165/Y1166); IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221] |
Gene, Accession # | [IGF-IR], Gene ID: 3480, NCBI: NP_000866.1, UniProt: P08069 |
Catalog # | MBS9701092 |
Price | $130, $220, $325 |
Order / More Info | IGF-IR (Phospho Tyr1165/Y1166) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |