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Antigenic Specificity | MEKK2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Mitogen-activated protein kinase kinase kinase 2(MAP3K2) detection. Tested with WB in Human, Mouse, Rat. Background: MAP3K2, mitogen-activated protein kinase kinase kinase 2, also known as MEKK2, belongs to the mitogen-activated protein kinase(MAPK) kinase kinase gene family, which is involved in regulating multiple MAPK signaling pathways. Endogenous MAP3K2 localized mainly to the cytosol of unstimulated HeLa cells and rat fibroblasts. The MAP3K2 gene is mapped to chromosome 2 by the International Radiation Hybrid Mapping Consortium. MAP3K2 is a major upstream activator of the JNK, MAPK cascade. MAP3K2 was identifies as 1 of 6 kinases that regulate different steps of the caveolar cycle. Silen |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human MEKK2 (606-619aa SADELLRHMFVHYH), different from the related rat and mouse sequences by one amino acid. |
Other Names | [Mitogen-activated protein kinase kinase kinase 2; mitogen-activated protein kinase kinase kinase 2; M3K2_HUMAN; Map3k2; MAPK/ERK kinase kinase 2; MEK kinase 2; MEKK 2; MEKK2b; Mitogen activated protein kinase kinase kinase 2; Mitogen-activated protein kinase kinase kinase 2], [MAP3K2; MAP3K2; MEKK2; MEKK2B; MAPKKK2; MEKK2; MEK kinase 2; MEKK 2] |
Gene, Accession # | [MAP3K2], Gene ID: 10746, NCBI: Q9Y2U5.2, UniProt: Q9Y2U5 |
Catalog # | MBS175490 |
Price | $280 |
Order / More Info | MEKK2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |