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Antigenic Specificity | Calreticulin |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity). |
Immunogen | Immunogen: A synthesized peptide derived from human Calreticulin - ER Marker. Subcellular Localization: Endoplasmic reticulum lumen. Cytoplasm, cytosol. Secreted, extracellular space, extracellular matrix. Cell surface. Sarcoplasmic reticulum lumen. Also found in cell surface (T cells), cytosol and extracellular matrix (PubMed: 10358038). Associated with the lytic granules in the cytolytic T-lymphocytes. |
Other Names | [Calreticulin; CRP55; Calregulin; Endoplasmic reticulum resident protein 60; ERp60; HACBP; grp60; CALR; CRTC], [CALR; CALR; RO; CRT; SSA; cC1qR; HEL-S-99n; CRTC; ERp60] |
Gene, Accession # | [CALR], Gene ID: 811, NCBI: NP_004334.1, UniProt: P27797 |
Catalog # | MBS179484 |
Price | $160, $340, $340 |
Order / More Info | Calreticulin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |