MLKL Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-MLKL antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | MLKL |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Peptide ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: MLKL Antibody detects endogenous levels of MLKL. Description: Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.Post Translational Modifications: Phosphorylation by RIPK3 induces a conformational switch that is required for necroptosis. It also induces homotrimerization and localization to the plasma membrane.Subunit Structure: Homotrimer; forms homotrimers on necroptosis induction. Interacts with RIPK3; the interaction is d |
| Immunogen | Immunogen: A synthesized peptide derived from human MLKL. |
| Other Names | [9130019I15Rik; FLJ34389; hMLKL; Mixed lineage kinase domain like; Mixed lineage kinase domain like protein; Mixed lineage kinase domain like pseudokinase; Mixed lineage kinase domain-like protein; Mlkl; MLKL_HUMAN] |
| Gene, Accession # | [MLKL], Gene ID: 197259, NCBI: NP_001135969.1, UniProt: Q8NB16 |
| Catalog # | MBS9611207 |
| Price | $225, $280, $340 |
| Order / More Info | MLKL Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies