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Antigenic Specificity | AFF4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Key component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by Key component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. In the SEC complex, AFF4 acts as a central scaffold that recruits other factors through direct interactions with ELL proteins (ELL, ELL2 or ELL3) and the P-TEFb complex. In case of infection by HIV-1 virus, the SEC complex is recruited by the viral Tat protein to stimulate viral gene expression. |
Immunogen | Immunogen: Recombinant human AF4/FMR2 family member 4 protein (77-334AA) |
Other Names | [AF4/FMR2 family member 4] |
Gene, Accession # | [AFF4], Gene ID: 27125, NCBI: NP_055238.1, UniProt: Q9UHB7 |
Catalog # | MBS7051509 |
Price | $160, $235 |
Order / More Info | AFF4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |