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Antigenic Specificity | KBTBD2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for KBTBD2 detection. Tested with WB, ICC/IF in Human; Mouse; Rat.Background: Kelch repeat and BTB domain containing 2 (KBTBD2), also known as BTB and kelch domain-containing protein 1, encodes a BTB-Kelch family subunit that p85alpha-specific recognition for the Cullin3-based E3 ubiqitin ligase complex, which regulates p85alpha protein ubiquitination and subsequently regulates phosphoinositide-3 kinases (PI3K) signaling. However, the expression profile and functional significance of Kbtbd2 is still largely unknown. The Human Protein Atlas which is an online source shows high Kbtbd2 expression in the spleen and thymus, suggesting that Kbtbd |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence of human KBTBD2 (QYDLELDRWSLRQHISERVLWDLGRDFR). |
Other Names | [Kelch repeat and BTB domain-containing protein 2; BTB and kelch domain-containing protein 1; KBTBD2; BKLHD1; KIAA1489; Kelch repeat and BTB domain containing 2] |
Gene, Accession # | [KBTBD2], Gene ID: 25948, NCBI: NP_056298.2, UniProt: Q8IY47 |
Catalog # | MBS1751527 |
Price | $315 |
Order / More Info | KBTBD2 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Zhang Z, Turer E, Li X, Zhan X, Choi M, Tang M, Press A, Smith SR, Divoux A, Moresco EM, Beutler B. Insulin resistance and diabetes caused by genetic or diet-induced KBTBD2 deficiency in mice. Proc Natl Acad Sci U S A. 2016 Oct 18; 113 (42):E6418-E6426. Epub 2016 Oct 5. |