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Antigenic Specificity | CD11C |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Integrin aX (CD11C, leukocyte surface antigen p150,95, CR4, Axb2) is a type 1 transmembrane protein that traditionally combines with 2 chain to form a leukocytespecific integrin known as inactivatedC3b (iC3b) receptor 4 (CR4). Integrin aX/ 2 shares similar properties of the aM/ 2 integrin in mediating adherence of neutrophils and monocytes to stimulated endothelial cells, and in phagocytosis of complement coated particles. Abnormal expression of Integrin aX is characteristic of hairy cell leukemia (HCL) and is dependent upon activation of protooncogenes Ras and JunD. Proteins and DNA elements that influence transcription of Integrin aX include Sp1 and Sp1like factors, AP1 family, C/EBP, Oct2 and PU.1. Integrin aX is present on monocyte deri |
Immunogen | Immunogen: A synthetic peptide of human cox2 |
Other Names | [ITGAX; ITGAX; CD11C; SLEB6; Integrin alphaX; CD11 antigenlike family memberC; Leu M5], [ITGAX; ITGAX; CD11C; SLEB6; CD11C] |
Gene, Accession # | Gene ID: 3687, NCBI: NP_000878.2, UniProt: P20702 |
Catalog # | MBS127903 |
Price | $200, $275, $430 |
Order / More Info | CD11C Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |