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Antigenic Specificity | BCMA Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. Protein Function: Receptor |
Immunogen | Immunogen: E Coli-derived human BCMA recombinant protein (Position: M1-A54). Subcellular Localization: Cell membrane; Perinuclear Golgi-like structures. Tissue Specificity: Expressed in mature B-cells, but not in T- cells or monocytes. |
Other Names | [Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; CD269; TNFRSF17; BCM; BCMA] |
Gene, Accession # | [BCMA], Gene ID: 608, NCBI: NP_001183.2, UniProt: Q02223 |
Catalog # | MBS1750544 |
Price | $315 |
Order / More Info | BCMA Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |