Mouse Bmi1, 136-163 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse Bmi1, 136-163
Clone[353CT22.4.4]
Host SpeciesMouse
Reactive Speciesmouse
IsotypeIgG2b
Formatunconjugated
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 1.85
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis Mouse Bmi1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 136-163 amino acids from mouse Bmi1. Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (By similarity). In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Immunogenn/a
Other Names[Polycomb complex protein BMI-1; Polycomb group RING finger protein 4; Bmi1; Bmi-1; Pcgf4]
Gene, Accession #[Bmi1], Gene ID: 12151, NCBI: NP_031578.2, UniProt: P25916
Catalog #MBS9200368
Price$165, $370
Order / More InfoMouse Bmi1, 136-163 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesPereira, J.D., et al. Proc. Natl. Acad. Sci. U.S.A. 107(36):15957-15962(2010) Chiba, T., et al. Hepatology 52(3):1111-1123(2010) Maertens, G.N., et al. EMBO J. 29(15):2553-2565(2010) Lee, K.S., et al. Oncogene 29(23):3349-3361(2010) Schaller, M.A., et al. PLoS ONE 5 (8), E12172 (2010) :
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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