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Antigenic Specificity | Human CD49d |
Clone | [Bu49] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | fluorescein (FITC) conjugate |
Size | 0.1 mg |
Concentration | IgG concentration 0.1mg/ml |
Applications | Flow cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Human CD49d monoclonal antibody, clone Bu49 recognizes human CD49d, also known as integrin alpha 4 or VLA-4 alpha subunit. CD49d is a 150kDa single pass type I transmembrane glycoprotein. CD49d can be proteolytically cleaved to yield framents of 80 and 70kDa (Hemler et al. 1987). CD49d associates with either CD29 to form VLA-4 or with Integrin beta-7 to form The Peyer patches-specific homing receptor LPAM-1, involved in the lymphocyte migration and homing to gut-associated lymphoid tissue (Sackstein 2006) through its interaction with MadCam-1, preferentially expressed on Peyer's patch high endothelial venules and postcapillary venules in lamina propria (Briskin et al. 1997). CD49d is expressed on a broad range of cells including |
Immunogen | n/a |
Other Names | [integrin alpha-4; Integrin alpha-4; integrin alpha-4; 269C wild type; CD49 antigen-like family member D; VLA-4 subunit alpha; antigen CD49D, alpha-4 subunit of VLA-4 receptor; integrin alpha 4; integrin alpha-4 subunit; integrin alpha-IV; very late activation protein 4 receptor, alpha 4 subunit; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor); CD49 antigen-like family member D; Integrin alpha-IV; VLA-4 subunit alpha; CD_antigen: CD49d], [ITGA4; ITGA4; IA4; CD49D; CD49D] |
Gene, Accession # | [CD49d], Gene ID: 3676, NCBI: NP_000876.3, UniProt: P13612 |
Catalog # | MBS210989 |
Price | $370 |
Order / More Info | Human CD49d Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |