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Antigenic Specificity | Alpha Synuclein |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a/k |
Format | unconjugated |
Size | 5 Control Slides, 0.1 mL (Concentrate), 3 ml (Prediluted) |
Concentration | n/a |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Alpha-synuclein is a 140 amino acids protein encoded by the SNCA gene. It is predominantly expressed in the neocortex, hippocampus, substantia nigra, thalamus, and cerebellum with smaller amounts are found in the heart, muscles, and other tissues. In the brain, alpha-synuclein is found mainly in presynaptic terminals. An alpha-synuclein fragment, known as the non-Abeta component (NAC) of Alzheimer's disease amyloid, originally found in an amyloid-enriched fraction, was shown to be a fragment of its precursor protein, NACP. Alpha-synuclein aggregates to form insoluble fibrils in pathological conditions characterized by Lewy bodies, such as Parkinson's disease, dementia with Lewy bodies and multiple system atrophy. These disorders are known a |
Immunogen | Immunogen: Recombinant protein of the human alpha synuclein. Localization: Cytoplasmic, Nuclear. Control: Brain, Breast, Skin, Tonsil, Bone Marrow, Alzheimer's Disease, Parkinson's Disease. Precautions: 1. This product contains sodium azide (NaN3), a toxic chemical which may react with plumbing to form highly explosive build-ups of metal azides. Upon disposal, flush with large volumes of water to prevent sodium azide build-up. 2. Ensure proper handling procedures are used with reagent. Always we |
Other Names | [alpha synuclein, partial; Alpha-synuclein; alpha-synuclein; synuclein alpha; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP], [SNCA; SNCA; PD1; NACP; PARK1; PARK4; NACP; PARK1; NACP] |
Gene, Accession # | Gene ID: 6622 |
Catalog # | MBS370326 |
Price | $130, $175, $185 |
Order / More Info | Alpha Synuclein Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |