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Antigenic Specificity | FGFR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | 0.55-0.75 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Affinity Purified Fibroblast Growth Factor Receptor 1 Antibody. Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1, 4, 5-trisphosphate. Phosphorylation of FRS2 |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 640-690 on human basic fibroblast growth factor receptor protein 1. Immunoglobulin: IgG. Expression: Detected in astrocytoma, neuroblastoma and adrenal cortex cell lines. Some isoforms are detected in foreskin fibroblast cell lines, however isoform 17, isoform 18 and isoform 19 are not detected in these cells. |
Other Names | [Basic fibroblast growth factor receptor 1; bFGF R; C FGR; CD 331; CEK; FGFBR; FGFR 1; Fibroblast growth factor receptor 1; FLG; FLG protein; FLT 2; FMS like tyrosine kinase 2; Fms related tyrosine kinase 2 Pfeiffer syndrome; Fms-like tyrosine kinase 2; HBGFR; Heparin binding growth factor receptor; HH2; HRTFDS; Hydroxyaryl protein kinase; KAL 2; MFR; N sam tyrosine kinase; N-SAM; OGD; Proto-oncogene c-Fgr; Tyrosylprotein kinase], [FGFR1; FGFR1; CEK; FLG; HH2; OGD; ECCL; FLT2; KAL2; BFGFR; CD331; FGFBR; FLT-2; HBGFR; N-SAM; FGFR-1; HRTFDS; bFGF-R-1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR; FGFR-1; BFGFR; bFGF-R-1; FLT-2] |
Gene, Accession # | [FGFR1], Gene ID: 2260, NCBI: AAA75007.1, UniProt: P11362 |
Catalog # | MBS540811 |
Price | $390 |
Order / More Info | FGFR1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |