FGFR1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFGFR1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat
Isotypen/a
Formatunconjugated
Size0.1 mg
Concentration0.55-0.75 ug/ul in antibody stabilization buffer
ApplicationsELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
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DescriptionAffinity Purified Fibroblast Growth Factor Receptor 1 Antibody. Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1, 4, 5-trisphosphate. Phosphorylation of FRS2
ImmunogenImmunogen: Synthetic peptide taken within amino acid region 640-690 on human basic fibroblast growth factor receptor protein 1. Immunoglobulin: IgG. Expression: Detected in astrocytoma, neuroblastoma and adrenal cortex cell lines. Some isoforms are detected in foreskin fibroblast cell lines, however isoform 17, isoform 18 and isoform 19 are not detected in these cells.
Other Names[Basic fibroblast growth factor receptor 1; bFGF R; C FGR; CD 331; CEK; FGFBR; FGFR 1; Fibroblast growth factor receptor 1; FLG; FLG protein; FLT 2; FMS like tyrosine kinase 2; Fms related tyrosine kinase 2 Pfeiffer syndrome; Fms-like tyrosine kinase 2; HBGFR; Heparin binding growth factor receptor; HH2; HRTFDS; Hydroxyaryl protein kinase; KAL 2; MFR; N sam tyrosine kinase; N-SAM; OGD; Proto-oncogene c-Fgr; Tyrosylprotein kinase], [FGFR1; FGFR1; CEK; FLG; HH2; OGD; ECCL; FLT2; KAL2; BFGFR; CD331; FGFBR; FLT-2; HBGFR; N-SAM; FGFR-1; HRTFDS; bFGF-R-1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR; FGFR-1; BFGFR; bFGF-R-1; FLT-2]
Gene, Accession #[FGFR1], Gene ID: 2260, NCBI: AAA75007.1, UniProt: P11362
Catalog #MBS540811
Price$390
Order / More InfoFGFR1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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