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Antigenic Specificity | Phospho-TAB1 (Tyr481) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, horse, sheep, rabbit, dog, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-TAB1(Tyr481) Antibody detects endogenous levels of TAB1 only when phosphorylated at Tyr481. Description: May be an important signaling intermediate between TGFB receptors and MAP3K7/TAK1. May play an important role in mammalian embryogenesis.Post Translational Modifications: Monoubiquitinated. Deubiquitinated by Y. enterocolitica YopP.Subunit Structure: Interacts with XIAP and BIRC7 (PubMed:17560374, PubMed:11865055). Interacts with TRAF6 and MAP3K7; during IL-1 signaling (PubMed:8638164, PubMed:10094049, PubMed:11323434). Identified in the TRIKA2 complex composed of MAP3K7, TAB1 and TAB2 (PubMed:11460167). |
Immunogen | Immunogen: A synthesized peptide derived from human TAB1 around the phosphorylation site of Tyr481. Tissue Specificity: Ubiquitous. |
Other Names | [2310012M03Rik; 3'-Tab1; MAP3K7IP 1; MAP3K7IP1; MGC57664; Mitogen activated protein kinase kinase kinase 7 interacting protein 1; Mitogen-activated protein kinase kinase kinase 7-interacting protein 1; TAB 1; TAB1; TAB1_HUMAN; TAK1 binding protein 1; TAK1-binding protein 1; TGF beta activated kinase 1 binding protein 1; TGF-beta activated kinase 1/MAP3K7 binding protein 1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; TGF-beta-activated kinase 1-binding protein 1; Transforming growth factor beta activated kinase binding protein 1] |
Gene, Accession # | [TAB1], Gene ID: 10454, NCBI: NP_006107, UniProt: Q15750 |
Catalog # | MBS9610430 |
Price | $225, $280, $340 |
Order / More Info | Phospho-TAB1 (Tyr481) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |