PLXNA2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPLXNA2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
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DescriptionSpecificity: PLXNA2 antibody detects endogenous levels of total PLXNA2. Function: Coreceptor for SEMA3A and SEMA6A. Necessary for signaling by SEMA6A and class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity).Subunit Structure: Homodimer. The PLXNA2 homodimer interacts with a SEMA6A homodimer, giving rise to a heterotetramer. Interacts directly with NRP1 and NRP2 (By similarity). Interacts
ImmunogenImmunogen: A synthesized peptide derived from human PLXNA2 Subcellular Location: Membrane. Tissue Specificity: Detected in fetal brain. Predicted Cross Reactivity: Pig, Zebrafish, Sheep, Rabbit, Dog, Chicken Similarity: Pig (100%), Zebrafish (82%), Sheep (92%), Rabbit (100%), Dog (100%), Chicken (83%)
Other Names[Plexin-A2; PlexinA2; PLXA2; PLXA2_HUMAN; PLXNA2; Semaphorin receptor OCT]
Gene, Accession #[PLXNA2], Gene ID: 5362, NCBI: NP_079455.3, UniProt: O75051
Catalog #MBS9610077
Price$240, $280
Order / More InfoPLXNA2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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