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Antigenic Specificity | PLXNA2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PLXNA2 antibody detects endogenous levels of total PLXNA2. Function: Coreceptor for SEMA3A and SEMA6A. Necessary for signaling by SEMA6A and class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity).Subunit Structure: Homodimer. The PLXNA2 homodimer interacts with a SEMA6A homodimer, giving rise to a heterotetramer. Interacts directly with NRP1 and NRP2 (By similarity). Interacts |
Immunogen | Immunogen: A synthesized peptide derived from human PLXNA2 Subcellular Location: Membrane. Tissue Specificity: Detected in fetal brain. Predicted Cross Reactivity: Pig, Zebrafish, Sheep, Rabbit, Dog, Chicken Similarity: Pig (100%), Zebrafish (82%), Sheep (92%), Rabbit (100%), Dog (100%), Chicken (83%) |
Other Names | [Plexin-A2; PlexinA2; PLXA2; PLXA2_HUMAN; PLXNA2; Semaphorin receptor OCT] |
Gene, Accession # | [PLXNA2], Gene ID: 5362, NCBI: NP_079455.3, UniProt: O75051 |
Catalog # | MBS9610077 |
Price | $240, $280 |
Order / More Info | PLXNA2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |