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Antigenic Specificity | CTH |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure. Acts as a cysteine-protein sulfhydrase by mediating sulfhydration of target proteins: sulfhydration consists of converting-SH groups into-SSH on specific cysteine residues of target proteins such as GAPDH, PTPN1 and NF-kappa-B subunit RELA, thereby regulating their f |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-405 of human CTH (NP 001893.2). |
Other Names | [Cystathionine gamma-lyase; Cystathionine gamma-lyase; cystathionine gamma-lyase; cystathionine gamma-lyase; Cysteine-protein sulfhydrase; Gamma-cystathionase] |
Gene, Accession # | [CTH], Gene ID: 1491, NCBI: P32929.3, UniProt: P32929 |
Catalog # | MBS8545916 |
Price | $280 |
Order / More Info | CTH Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |