AIF1/Iba1 (Microglia Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAIF1/Iba1 (Microglia Marker)
Clone[AIF1/1909]
Host SpeciesMouse
Reactive Specieshuman.
IsotypeIgG1, kappa
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) Formalin
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DescriptionSpecificity: AIF1 is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).
ImmunogenImmunogen: Purified recombinant human AIF1 protein (around aa 1-146). Cellular Localization: Cytoplasmic and Cell Surface
Other Names[Allograft inflammatory factor 1 (AIF1); balloon angioplasty responsive transcription (BART1); IBA1; Interferon responsive transcript 1; Ionized calcium-binding adapter molecule 1; IRT1; Microglia response factor (MRF1)], [Iba1]
Gene, Accession #[AIF1], Gene ID: 199, NCBI: NP_001305899.1, UniProt: P55008
Catalog #MBS439927
Price$190, $340, $340
Order / More InfoAIF1/Iba1 (Microglia Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesKelemen SE, Autieri MV.Expression of allograft inflammatory factor-1 in T lymphocytes.Am J Pathol2005; 167:619-26.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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