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Antigenic Specificity | AIF1/Iba1 (Microglia Marker) |
Clone | [AIF1/1909] |
Host Species | Mouse |
Reactive Species | human. |
Isotype | IgG1, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: AIF1 is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC). |
Immunogen | Immunogen: Purified recombinant human AIF1 protein (around aa 1-146). Cellular Localization: Cytoplasmic and Cell Surface |
Other Names | [Allograft inflammatory factor 1 (AIF1); balloon angioplasty responsive transcription (BART1); IBA1; Interferon responsive transcript 1; Ionized calcium-binding adapter molecule 1; IRT1; Microglia response factor (MRF1)], [Iba1] |
Gene, Accession # | [AIF1], Gene ID: 199, NCBI: NP_001305899.1, UniProt: P55008 |
Catalog # | MBS439927 |
Price | $190, $340, $340 |
Order / More Info | AIF1/Iba1 (Microglia Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Kelemen SE, Autieri MV.Expression of allograft inflammatory factor-1 in T lymphocytes.Am J Pathol2005; 167:619-26. |