ATM Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityATM
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsImmunohistochemistry (IHC) Paraffin, ELISA (EIA)
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DescriptionSpecificity: Atm Polyclonal Antibody detects endogenous levels of Atm protein. The protein encoded by ATM belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.
ImmunogenImmunogen: Synthesized peptide derived from human Atm around the non-phosphorylation site of S1981
Other Names[Rabbit Atm; ATM; Serine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated]
Gene, Accession #[ATM], Gene ID: 472, NCBI: AAI37170.1, UniProt: Q13315
Catalog #MBS9705984
Price$130, $220, $325
Order / More InfoATM Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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