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Antigenic Specificity | MANF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody does not cross-react with CDNF. MANF Antibody: MANF, also known as ARMET, was initially identified as a protein containing an arginine-rich region that was highly mutated in a variety of tumors. More recently it was identified as a mesencephalic astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons, similar to glial cell line-derived neurotrophic factor (GDNF) and CDNF. In rat brain slices, MANF enhanced nigral gamma-aminobutyric acid release. Like GDNF and CDNF, MANF has selective neuroprotective activity for dopaminergic neurons suggesting that it may be indicated for the treatment of Parkinson's disease. Expression of MANF has also been shown to be induced during ER stress, suggesting that it may p |
Immunogen | Immunogen: MANF antibody was raised against a 12 amino acid synthetic peptide from near the carboxy terminus of human MANF. Buffer: MANF Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [MANF; ARP; ARMET; ARP; Mesencephalic astrocyte-derived neurotrophic factor; Arginine-rich protein; arginine-rich, mutated in early stage tumors], [MANF; MANF; ARP; ARMET; ARMET; ARP] |
Gene, Accession # | [ARMET], Gene ID: 7873, NCBI: P55145.2, UniProt: P55145 |
Catalog # | MBS151013 |
Price | $375 |
Order / More Info | MANF Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |