VAV1 - middle region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityVAV1 - middle region
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciescow, dog, horse, human, mouse, porcine, rabbit, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis is a rabbit polyclonal antibody against VAV1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: This protein is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication.The protein encoded by this proto-oncogen
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the middle region of human VAV1
Other Names[proto-oncogene vav isoform 1; Proto-oncogene vav; proto-oncogene vav; vav guanine nucleotide exchange factor 1]
Gene, Accession #[VAV1], Gene ID: 7409, NCBI: NP_005419, UniProt: P15498
Catalog #MBS3224563
Price$335
Order / More InfoVAV1 - middle region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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