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Antigenic Specificity | SLC1A2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.7 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total SLC1A2 protein. This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to residues near the C terminal of human solute carrier family 1 (glial high affinity glutamate transporter), member 2 |
Other Names | [EAAT2; GLT-1] |
Gene, Accession # | [SLC1A2], Gene ID: 6506, NCBI: NP_001182657.1, UniProt: P43004 |
Catalog # | MBS9409905 |
Price | $255 |
Order / More Info | SLC1A2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |