MEN1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | MEN1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: MEN1 antibody detects endogenous levels of total MEN1. Function: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity). May be involved in DNA repair.Subun |
| Immunogen | Immunogen: A synthesized peptide derived from human MEN1 Subcellular Location: Nucleus. Concentrated in nuclear body-like structures. Relocates to the nuclear matrix upon gamma irradiation. Tissue Specificity: Ubiquitous. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Dog, Xenopus Similarity: Pig (100%), Zebrafish (100%), Bovine (100%), Horse (92%), Dog (100%), Xenopus (92%) |
| Other Names | [MEA 1; MEA1; MEN 1; Men1; MEN1_HUMAN; Menin; Multiple Endocrine Adenomatosis 1; Multiple Endocrine Neoplasia 1; SCG 2; SCG2; Suppressor Candidate Gene 2; Wermer syndrome; ZES; Zollinger Ellison Syndrome] |
| Gene, Accession # | [MEN1], Gene ID: 4221, NCBI: NP_000235.2, UniProt: O00255 |
| Catalog # | MBS9601458 |
| Price | $240, $280 |
| Order / More Info | MEN1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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