TLR3 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | TLR3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Members of the Toll-like receptor (TLR) family, named for the closely related Toll receptor in Drosophila, play a pivotal role in innate immune responses (1-3). TLRs recognize conserved motifs found in various pathogens and mediate defense responses. Triggering of the TLR pathway leads to the activation of NF-kappaB and subsequent regulation of immune and inflammatory genes. The TLRs and members of the IL-1 receptor family share a conserved stretch of approximately 200 amino acids known as the TIR domain. Upon activation, TLRs associate with a number of cytoplasmic adaptor proteins containing TIR domains including MyD88 (myeloid differentiation factor), MAL/TIRAP (MyD88-adaptor-like/TIR-associated protein), TRIF (Toll-receptor-associated ac |
| Immunogen | Immunogen: Recombinant protein of human TLR3 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [TLR3; CD283] |
| Gene, Accession # | [TLR3], Gene ID: 7098, NCBI: NP_003256.1, UniProt: O15455 |
| Catalog # | MBS8500731 |
| Price | $310 |
| Order / More Info | TLR3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Akira, S. (2003) J Biol Chem 278, 38105-8. 2. Beutler, B. (2004) Nature 430, 257-63. 3. Dunne, A. and O'Neill, L.A. (2003) Sci STKE 2003, re3. 4. Alexopoulou, L. et al. (2001) Nature 413, 732-8. 5. Muzio, M. et al. (2000) J Immunol 164, 5998-6004. 6. Nishimura, M. and Naito, S. (2005) Biol Pharm Bull 28, 886-92. 7. Matsumoto, M. et al. (2003) J Immunol 171, 3154-62. 8. Funami, K. et al. (2007) J Immunol 179, 6867-72. 9. Hoebe, K. et al. (2003) Nat Immunol 4, 1223-9. 10. Oshiumi, H. et al. (2003) Nat Immunol 4, 161-7. 11. Sasai, M. et al. (2010) Mol Immunol 47, 1283-91. 12. Meylan, E. et al. (2004) Nat Immunol 5, 503-7. 13. Jiang, Z. et al. (2004) Proc Natl Acad Sci USA 101, 3533-8. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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