Edit |   |
Antigenic Specificity | phospho-Sox2 (S246) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.45 |
Applications | Immunofluorescence (IF), Dot Blot (DB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Sox2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S246 of human Sox2. This intronless gene encodes a member of the SRY-relatedHMG-box (SOX) family of transcription factors involved in theregulation of embryonic development and in the determination ofcell fate. The product of this gene is required for stem-cellmaintenance in the central nervous system, and also regulates geneexpression in the stomach. Mutations in this gene have beenassociated with optic nerve hypoplasia and with syndromicmicrophthalmia, a severe form of structural eye malformation. Thisgene lies within an intron of another gene called SOX2 ove |
Immunogen | n/a |
Other Names | [Transcription factor SOX-2; SOX2] |
Gene, Accession # | [SOX2], Gene ID: 6657, NCBI: NP_003097.1, UniProt: P48431 |
Catalog # | MBS9206432 |
Price | $165, $370 |
Order / More Info | phospho-Sox2 (S246) Antibody from MYBIOSOURCE INC. |
Product Specific References | References for protein: 1.Gen, Y., et al. Cancer Genet. Cytogenet. 202(2):82-93(2010) 2.Ji, J., et al. Hum. Pathol. 41(10):1438-1447(2010) 3.Fang, X., et al. OMICS 14(4):369-384(2010) 4.Sholl, L.M., et al. Am. J. Surg. Pathol. 34(8):1193-1198(2010) 5.Zhang, D., et al. BMC Med. Genet. 11, 116 (2010) References for SY5Y (SH-SY5Y; ATCC#CRL-2266): 1. Ross RA, et al. Coordinate morphological and biochemical interconversion of human neuroblastoma cells. J. Natl. Cancer Inst. 71: 741-749, 1983. [PubMed: 6137586]; 2. Biedler JL, et al. Multiple neurotransmitter synthesis by human neuroblastoma cell lines and clones. Cancer Res. 38: 3751-3757, 1978. [PubMed: 29704]. |