Edit |   |
---|---|
Antigenic Specificity | Granzyme B/H |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Granzyme B/H Polyclonal Antibody detects endogenous levels of Granzyme B/H protein. GZMH encodes a member of the peptidase S1 family of serine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a chymotrypsin-like protease. Granzyme H is reported to be constitutively expressed in the NK (natural killer) cells of the immune system and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. GZMH is present in a gene cluster with another member of the granzyme subfamily on chromosome 14. |
Immunogen | Immunogen: Synthesized peptide derived from the N-terminal region of human Granzyme B/H at AA rangle: 10-90 |
Other Names | [Rabbit Granzyme B/H; CGL1; CSPB; CTLA1; GRB; Granzyme B; C11; CTLA-1; Cathepsin G-like 1; CTSGL1; Cytotoxic T-lymphocyte proteinase 2; Lymphocyte protease; Fragmentin-2; Granzyme-2; Human lymphocyte protein; HLP; SECT; T-cell serine protease 1-3E; GZMH; C] |
Gene, Accession # | [GZMB], Gene ID: 3002, NCBI: NP_004122.2, UniProt: P10144 |
Catalog # | MBS9705346 |
Price | $130, $220, $325 |
Order / More Info | Granzyme B/H Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |