Human CD279(PD-1) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Human CD279(PD-1) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Human CD279(PD-1) |
| Clone | [ANC4H6] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1k |
| Format | no preservative |
| Size | 0.1 mg |
| Concentration | 1.0 mg/ml |
| Applications | Flow Cytometry (FC/FACS), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Information: Human CD279 (PD-1, Programmed death 1) is a 55 kd Ig superfamily member with sililarity to CD28 and CD152(CTLA-4). It is expressed on activated T and B and myeloid cells, and engagement by its ligands PD-L1 (CD274, B7-H1) or PD-L2 (B7-DC) can inhibit proliferation and cytokine expression. In mice blockade of PD-1 ligand interaction has been used to augment T cell anti cancer responses (3,4,5). Anti-CD279 antibody clone ANC4H6 binds to CD279 present on PHA activated PBMC in FACS, and binds to recombinant CD279 in EIA. |
| Immunogen | Immunogen: Recombinant human 279 |
| Other Names | n/a |
| Gene, Accession # | [CD279] |
| Catalog # | MBS666020 |
| Price | $270 |
| Order / More Info | Human CD279(PD-1) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1) Ishida et al. (1992) EMBO J 11(11):3887-95. 2) Carreno BM, M Collins, et al. (2001) Annu Rev Immunol 20:29. 3) MA Curran, Allison JP, et al. (2010) PNAS 107(9): 4275-80. 4) Mangsbo SM, TH Totterman, et al. (2010) J Immunotherapy 33(3):225. 5) Hirano F, L Chen, et al. (2005) Canc Res 65: 1089. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies